PANCREAS-SPECIFIC SIRT1-DEFICIENCY IN MICE COMPROMISES BETA-CELL FUNCTION WITHOUT DEVELOPMENT OF HYPERGLYCEMIA.

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia.

Sirtuin 1 (Sirt1) has been reported to be a critical positive regulator of glucose-stimulated insulin secretion in pancreatic beta-cells.The effects on islet cells and blood glucose levels when Sirt1 RED CHESTNUT is deleted specifically in the pancreas are still unclear.This study examined islet glucose responsiveness, blood glucose levels, pancrea

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Hemophagocytic Lymphohistiocytosis Associated with Coinfection of Scrub Typhus and Dengue Fever in a Child: A Case Report

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon life-threatening immune disorder that may be either primary or secondary to infection, malignancy, or rheumatological disease.In tropical countries like India, secondary HLH is more commonly seen.Both Dengue fever and scrub typhus, which result in more than half of all acute undifferentiated f

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Ultrasensitive terahertz sensing with high-Q toroidal dipole resonance governed by bound states in the continuum in all-dielectric metasurface

Toroidal dipole (TD) with weak coupling to 3 IN1 UNSCENTED LOTION the electromagnetic fields offers tremendous potential for advanced design of photonic devices.However, the excitation of high quality (Q) factor TD resonances in these devices is challenging.Here, we investigate ultrahigh-Q factor TD resonances at terahertz frequencies arising from

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